Insights on the mechanisms that underlie muscle atrophy in DM are provided by studies in a new mouse model.
The RNA binding protein, rbFOX1, competes with MBNL in binding to CCUGexp, but not CUGexp repeats, and thereby mitigates DM2.
The review journal, Frontiers in Neurology, is publishing six new articles on myotonic dystrophy.
Two Ocean Creek in Wyoming’s Teton wilderness holds a special place for Joel Revill. The creek cuts along the Continental Divide and snow that melts into the creek has an equal chance of flowing to either the Atlantic or Pacific Oceans. The area was a favorite place for Joel to fish, hike, and backpack while he was growing up in Powell, Wyoming, a rural area about 25 miles northeast of Cody.
MDF updates information on the Department of Defense’s Peer Reviewed Medical Research Program first described in the April Research News.
NINDS has a strong program to support preclinical therapy development and has released three additional initiatives to support work in academia or industry.
Intronic GC-rich microsatellite expansions are common in neurological disorders and act to trigger the intronic retention that underlies disease pathogenesis.