Methodology is reported for robust and reliable quantification of mutant and abberantly spliced RNA in cells from DM patients.
News
05/03/2018 - 8:37am
Some of you may have watched the news show, 60 Minutes, on April 29th. The 60 Minutes piece of interest to everyone with an inherited disease, like DM, was titled: “CRISPR: The Gene-Editing Tool Revolutionizing Biomedical Research”.
05/03/2018 - 8:06am
When cardiologist Dr. William J. Groh examined a young woman with an arrhythmia in 1995, he thought it was unusual. She did not have known heart disease or heart failure that would normally be associated with a serious heart rhythm disturbance. What she did have, though, was myotonic dystrophy (DM).
04/10/2018 - 1:47pm
Human iPSC-derived cardiomyocytes recapitulate some features of the DM1 heart.
04/09/2018 - 4:51pm
Subcellular compartmentalization of MBNL1 plays a key role in regulation of neurite differentiation and its disruption may contribute to CNS defects in DM.
