A generic cardiovascular drug called mexiletine, initially developed to treat heart rhythm abnormalities, appears to hold some potential for treating muscle stiffness and other symptoms of non-dystrophic myotonias (NDMs),
Circular RNAs that play a role in myogenesis are dysregulated in DM1 skeletal muscle.
A new study examines approaches to determine DM1 study subject progenitor allele length.
Multivalent ligands show bioavailability and efficacy in targeting splicing defects in DM1.
Antisense oligonucleotides – short segments of genetic material designed to target specific areas of a gene
The new approach could have implications for many genetic diseases.
ROSEVILLE, CA (January 25, 2012): MDF is pleased to announce its largest-ever round of Fund-A-Fellow postdoctoral fellowship research grant awards.
