Myotonic dystrophy (DM) can affect all age groups, and people living with DM often have different symptoms at different ranges of severity. DM can also affect a range of systems, so symptom management requires a more expansive approach. You’ll likely need to coordinate with a multidisciplinary team to provide comprehensive care. Here’s an article that shows the range of specialists you might work with, and what they’re focus will be.
Click on the arrows by each body system below to expand descriptions. For Medical Professionals: Each "Deep Dive" section includes specific clinical care recommendations.
- Heart rhythm problems (arrhythmias)
- Enlarged heart muscle
- Low blood pressure
- Sudden death
Cardiovascular System
- Heart rhythm problems (arrhythmias)
- Enlarged heart muscle
- Low blood pressure
- Sudden death
- Difficulty with thinking and problem solving
- Emotional and behavior problems
- Excessive daytime sleepiness
- Nerve damage in feet and hands
Brain
- Difficulty with thinking and problem solving
- Emotional and behavior problems
- Excessive daytime sleepiness
- Nerve damage in feet and hands
- Small testes, low sperm count, low testosterone
- Higher risk of miscarriage and stillbirth; early menopause
- Problems with pregnancy and delivery
- Newborn complications
Reproductive System
- Small testes, low sperm count, low testosterone
- Higher risk of miscarriage and stillbirth; early menopause
- Problems with pregnancy and delivery
- Newborn complications
- Cataracts
- Damage to the retina
- Drooping eyelids (ptosis)
Vision
- Cataracts
- Damage to the retina
- Drooping eyelids (ptosis)
- Higher risk of benign skin tumor (pilomatrixoma)
- Alopecia
- Dysplastic nevi
- Seborrheic dermatitis
Skin
- Higher risk of benign skin tumor (pilomatrixoma)
- Alopecia
- Dysplastic nevi
- Seborrheic dermatitis
- Breathing problems in newborns
- Frequent lung infections
- Aspiration of food or fluids into airways
- Inability to breathe in enough oxygen
- Sleep apnea
Respiratory System
- Breathing problems in newborns
- Frequent lung infections
- Aspiration of food or fluids into airways
- Inability to breathe in enough oxygen
- Sleep apnea
- Difficulty swallowing
- Pain and bloating after meals
- Constipation, diarrhea, irritable bowel syndrome, gastrointestinal reflux
- Gallstones
- Enlarged colon
Gastrointestinal System
- Difficulty swallowing
- Pain and bloating after meals
- Constipation, diarrhea, irritable bowel syndrome, gastrointestinal reflux
- Gallstones
- Enlarged colon
- Insulin resistance
- Premature frontal balding in men
Endocrine
- Insulin resistance
- Premature frontal balding in men
- Muscle weakness (myopathy)
- Muscle stiffness and trouble relaxing a muscle (myotonia)
- Muscle wasting that gets worse over time (atrophy)
- Severe muscle weakness and delayed development in newborns and infants
Muscle
- Muscle weakness (myopathy)
- Muscle stiffness and trouble relaxing a muscle (myotonia)
- Muscle wasting that gets worse over time (atrophy)
- Severe muscle weakness and delayed development in newborns and infants
- Inherited disease, autosomal-dominant mutation
- 50% chance of passing mutated gene to each child
- More severe with each generation ("anticipation")
Genetics
- Inherited disease, autosomal-dominant mutation
- 50% chance of passing mutated gene to each child
- More severe with each generation ("anticipation")