Endocrine Function Over Time in Patients with Myotonic Dystrophy Type 1

Dr. John Vissing and his colleagues at the University of Copenhagen recently tracked a group of 68 adults with myotonic dystrophy type 1 (DM1), measuring their endocrine function change over 8 years.

Toxic RNA Research Update

Researchers from Dr. Matthew Disney's lab at the Scripps Research Institute of Florida recently published an article describing a new chemical they designed to inhibit the unhealthy repeat-containing RNA molecule seen in DM2.

Parental Age Effects in the Transmission of DM1

New research on the impact of the mother's age on congenitally affected offspring.

Promising Small Molecule Study for DM2

Researchers at the University of Illinois recently re-engineered small molecules to disrupt toxic RNA repeats involved in DM2.


The DMCRN was established a little over three years ago to evaluate potential DM treatments, prepare possible clinical trial sites and conduct important DM research studies.

Ionis Launches Phase 1 Trial of IONIS-DMPK Rx to Treat DM1

Ionis Pharmaceuticals, Inc. (formerly Isis Pharmaceuticals, Inc.) announced today that it has launched a Phase 1 clinical trial for IONIS-DMPKRX. IONIS-DMPKRX is designed to reduce the production of toxic dystrophia myotonic-protein kinase (DMPK) RNA in cells, including muscle cells, for the treatment of Myotonic Dystrophy Type 1 (DM1).

DM2 Patients and Statins

Researchers identify the gene believed to be responsible for adverse statin drug side effects in DM2 patients.  

Stanford University Myotonic Dystrophy Biobank

Stanford University has launched the DM Biobank to provide high-quality DM biological samples to researchers around the world. By participating in the Biobank, DM community members can play an important role in the development of new therapies that may help patients today and for generations to come.

Interesting Findings Reported in Recent DM Research Studies on Sleep Disturbances

Interesting Findings Reported in Recent DM Research Studies on Sleep Disturbances

Interesting Findings Reported in Recent DM Research Studies on Facial Recognition

A recently published study from Sweden reported impaired facial recognition in people with DM1 and indicated that there are brain differences that affect how faces are perceived and stored by people with DM1.

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